Vivafree™ Centrifugal Filters

Vivafree centrifugal filters offer fast, accurate separations of free drugs for Therapeutic Drug Monitoring. They have been used successfully for phenytoin1, valproic acid, antibiotics, immunosuppressants and other drugs. Vivafree™ filters are also being used clinically to separate free hormones such as testosterone and insulin. Separations can be performed as quickly as 20 minutes with high recoveries and excellent reproducibility. Savings of 35% have been reported when switching to Vivafree™ filters from another centrifugal ultrafiltration device2.

These devices are used for a variety of applications by clinical diagnostic labs. Vivaproducts also provides pipettes and centrifuges for use with these filters.

(1) Comparison of Centrifugal Filter Performance for Free Phenytoin Assays (PDF)

(2) Evaluation of a Centrifugal Filtration Device in the Measurement of Free Testosterone (PDF)

Vivafree™ 2

Vivafree 2 Vivafree™ 2

Up to 2 ml starting sample volume

For separation of free drugs and hormones from those bound to serum proteins.

Vivafree™ 500

Vivafree 500 Vivafree™ 500

Up to 500 µl starting sample volume

For separation of free drugs and hormones from those bound to serum proteins.

 

Drug & Hormone Separations

Free Drug & Hormone Separations with Vivafree™ Filters

Vivafree™ filters can be used to prepare samples for therapeutic drug monitoring of phenytoin, valproic acid and digoxin. They can also separate free testosterone, insulin and cortisol in clinical samples.

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