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Viva Products - Protein Purification and Separation Technologies

Vivafree™ Centrifugal Filters

Vivafree™ centrifugal filters offer fast, accurate separations of free drugs for Therapeutic Drug Monitoring. They have been used successfully for phenytoin1, valproic acid, antibiotics, immunosuppressants and other drugs. Vivafree™ filters are also being used clinically to separate free hormones such as testosterone and insulin. Separations can be performed as quickly as 20 minutes with high recoveries and excellent reproducibility. Savings of 35% have been reported when switching to Vivafree™ filters from another centrifugal ultrafiltration device2. These devices are intended for in vitro diagnostic (IVD) applications. Vivaproducts also provides centrifuges for use with these filters.

Products

Vivafree™ 2 Centrifugal Filter

Vivafree™ 2 Centrifugal Filter

Up to 2 ml starting sample volume

For separation of free drugs and hormones from those bound to serum proteins.
Vivafree™ 500 Centrifugal Filter

Vivafree™ 500 Centrifugal Filter

Up to 500 µl starting sample volume

For separation of free drugs and hormones from those bound to serum proteins.

Free Drug & Hormone Separations with Vivafree™ Filters

Download this Applications Note to see how Vivafree™ filters can be used to prepare samples for therapeutic drug monitoring of phenytoin, valproic acid and digoxin. They can also separate free testosterone, insulin and cortisol in clinical samples.

Comparison of Centrifugal Filter Performance for Free Phenytoin

Download a poster from an AACC Annual Meeting comparing the Vivafree™ and Centrifree® filters for free phenytoin sample preparation.

Evaluation of a Centrifugal Filtration Device to Measure Free Testosterone

Download a presentation from an AACC Annual Meeting comparing the Vivafree™ and Centrifree® filters for free testosterone sample preparation.

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